
Not every organization gets to “move fast and break things.” In regulated industries, the momentum behind tech modernization must be balanced with mission, risk, and public trust. How do you walk that line?
Hosted by Stuart Brown, Guidehouse Global Technology Leader, The GuideLine tackles that question through candid interviews with both the regulated and the regulators: industry executives managing complex systems, public sector innovators shaping oversight and mission outcomes, and senior technologists translating requirements into architecture. Together, they unpack what’s changing as AI and other emerging tools move into the daily operations of high-accountability enterprises.
The focus stays practical: what to build, what to scale, and what to rethink. Expect a mix of big-picture strategy and technical depth, along with actionable advice for those moving fast, but carefully, with today’s tech.
Not every organization gets to “move fast and break things.” In regulated industries, the momentum behind tech modernization must be balanced with mission, risk, and public trust. How do you walk that line?
Hosted by Stuart Brown, Guidehouse Global Technology Leader, The GuideLine tackles that question through candid interviews with both the regulated and the regulators: industry executives managing complex systems, public sector innovators shaping oversight and mission outcomes, and senior technologists translating requirements into architecture. Together, they unpack what’s changing as AI and other emerging tools move into the daily operations of high-accountability enterprises.
The focus stays practical: what to build, what to scale, and what to rethink. Expect a mix of big-picture strategy and technical depth, along with actionable advice for those moving fast, but carefully, with today’s tech.
Episodes

Monday Jun 15, 2026
The moment has come for government CIOs
Monday Jun 15, 2026
Monday Jun 15, 2026
For federal chief information officers, this is a moment of pressure, but also possibility. Today’s government tech leaders are being asked to move faster, deliver better services, and roll out AI responsibly, all at once. In this episode of The GuideLine, Stuart Brown talks with Nancy Sieger, former Chief Information Officer of the IRS and former Chief Technology Officer at the U.S. Department of the Treasury, about what this triple mandate means for CIOs working within U.S. federal agencies.
Together, Stu and Nancy examine the growing tension between innovation and governance, and why user experience is becoming a defining responsibility of the CIO role. They discuss what practical AI adoption looks like in government, why experimentation within guardrails builds momentum, and how citizen developers help turn ideas into action. The conversation also explores the future of tech talent within government, and why federal agencies may be uniquely positioned to leapfrog into new ways of working in the AI era.

Monday May 11, 2026
Moonshot first, then tools: The way to AI value
Monday May 11, 2026
Monday May 11, 2026

Monday Apr 13, 2026
The enterprise is changing. Are we?
Monday Apr 13, 2026
Monday Apr 13, 2026
Agentic AI is rewriting the rules of work—and not in the way most organizations are talking about it. In this inaugural episode of The GuideLine, Stuart Brown (Stu) speaks with Microsoft Corporate Vice President Ulrich Homann (Uli) about why the agentic shift is bigger than a technology upgrade or even a change-management effort. At its core, Uli argues, it reshapes how decisions get made, how work gets done, and what an enterprise really is.
Stu and Uli map the foundations behind AI, share a three part framework for understanding agentic systems, and explain what Microsoft calls the “frontier firm.” Along the way, they dig into the practical realities that leaders can’t ignore: data sovereignty, the enterprise memory layer, and the line between automating tasks and building truly intelligent workflows. They wrap with a candid look at what’s next for organizations, and for a workforce stepping into a world where AI agents are part of the team.
The GuideLine is brought to you by Guidehouse. © 2026 Guidehouse.
